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中藥愈白湯熏洗坐浴治療外陰上皮內非瘤樣病變的研究

本篇論文轉自論文下載網 www.Lunwenda.com 版權歸原作者所有 原文鏈結：https://www.lunwenda.com/yiyao200902/104833-2/目的: 研究治療外陰上皮內非瘤樣病變的新方法。方法: 將93例該病患者隨機分為實驗組和對照組，實驗組病人68例採用自製中藥方劑愈白湯水煎坐浴，每日三次，每次 30min，三個月為一療程。對照組25例採用膚輕鬆軟膏及丙酸睾丸素外塗。結果: 實驗組病人68例，治癒52例，治癒率7647%；有效10例，有效率1471%；總有效率9118%。對照組病人25例,治癒1例,治癒率4%；有效10例,有效率40%；總有效率44%。結論: 愈白湯治療外陰上皮內非瘤樣病變效果顯著，且無毒副作用，可推廣使用。

    【關鍵字】  外陰上皮內非瘤樣病變; 愈白湯

    【ABSTRACT】  Objective: To investigate the new therapy for nonneoplastic epithelial disorders of skin and mncosa. Methods: 25 patients in the control group were applied to ointment with fluocinoloni acetonidum and oinment with testosterone propionate,and 68 patients in the research group took hip bath with Chinese traditional medicine Yubai Tang to clean the genital organs, three times every day,30 minutes every time, and three months were taken as a period of treatment. Results: In the research group, there were 52 patients who had been cured,the cured ratio was 7647%, 10 patients had effect,the effect ratio was 1471%,and so the total effect ratio was 9118%. In the control group,there was 1 patient who had been cured (cured ratio 4%),10 patients had effect (effect ratio 40%),the total effect ratio was 44%. So it is remarkably significant to compare the curative effects for the two groups（P<001 ）. Conclusion： Traditional Chinese medicine Yubai Tang has obvious therapeutic effect on nonneoplastic epithelial disorders of skin and mncosa without poisonous and ill effect, and so this kind of new therapy can be generalized.

    【KEY WORDS】  Nonneoplastic epithelial disorders of skin and mncosa; Yubai Tang

    外陰上皮內非瘤樣病變是女性外陰皮膚和粘膜組織發生變性及色素改變的一組慢性疾病。因病變部位皮膚和粘膜多呈白色，故又稱其為外陰白色病變。本病病程較長，復發率高，目前無特效治療方法。為研究治療此病的新方法，我們將20031~200512月於河北省懷來縣醫院門診就診的患此病病人93例，隨機分對照組和實驗組進行觀察治療；對照組25例採用膚輕鬆軟膏及丙酸睾丸素外塗；實驗組68例病人給予中藥愈白湯治療，結果報導如下[1，2]。

    1  資料與方法

    11  一般資料  河北省懷來縣醫院20031~200512月門診經病理檢查確診為本病的93例病人,隨機分為兩組。實驗組68例，採用中藥愈白湯坐浴治療；對照組25 例，局部外用膚輕鬆及丙酸睾丸素軟膏。93例病人中，硬化性苔癬50例，鱗狀上皮細胞增生43例，兩組病人年齡、病程、病理分型上均無顯著性差異（P<005）。

    12  方法  中藥愈白湯由以下中藥組成:黃芪 60g、淫羊藿 30g、丹參 20g、野百合 20g、山慈姑 10g、蒼術 20g、生地 20g、白花蛇舌草 30g、赤勺 20g、白術 20g、黃柏 20g、地膚子 20g、土茯苓 30g。以上藥物布包水煎,熏洗坐浴,每日2~3次，每次30min，3個月為一療程。對照組外陰塗擦膚輕鬆軟膏及丙酸睾丸素軟膏，每日一次，30d為一療程。

本篇論文轉自論文下載網 www.Lunwenda.com 版權歸原作者所有 原文鏈結：https://www.lunwenda.com/yiyao200902/104833/ 

 13  療效判定標準  痊癒:症狀消失, 外陰皮膚粘膜顏色、彈性基本恢復正常，病理檢查為“正常皮膚和粘膜”。有效：症狀消失，原白色病變區域縮小、變紅，或部分轉為褐色。無效：症狀無緩解，病變區皮膚面積未縮小或反而增大[3,4]。

    1４  統計方法  採用χ2檢驗(論文下載網 www.lunwenda.com )

本篇論文轉自論文下載網 www.Lunwenda.com 版權歸原作者所有 原文鏈結：https://www.lunwenda.com/yiyao200902/104833-2/